The “Nemesis Detective Agency” members that, conversely and magnificently, exposed a deplorable crime by the expose video creator Tajimin: detective assistant Mikami Anna (Hirose Suzu), self-proclaimed great detective Kazama Naoki (Sakurai Sho), and boss Kurita Kazuaki (Eguchi Yosuke). This time’s client is journalist Kanda Nagisa (Maki Yoko), who fought together with Nemesis to capture Tajimin. Kanda Nagisa is the younger sister of Kazama’s former colleague Kanda Mizuho (Maki Yoko / dual role), who died together with Mima Meiko (Yamazaki Hirona) in an accident caused by Anna’s currently missing father Hajime (Nakamura Toru).
Nagisa’s request is for them to identify the true identity of the consultant company president Karasuma (Uno Shohei), who covered up the “Mysterious Clinical Trial Death” case that Nagisa had been working on. Kurita, believing that Karasuma and the Kan Research Institute are connected, accepts the request on the basis that Nagisa doesn’t tell Anna of the incident 20 years ago, and they set out on the investigation.
Kazama immediately investigates Karasuma’s behaviour, however he finds him only ever on the phone with people, wherever he goes. Furthermore, muscular bodyguard Shiba (Itabashi Shunya) is around at all times, meaning he couldn’t get anywhere near. However, Kazama discovers that Karasuma goes to an illegal gambling den every week, and Kurita orders him to steal the data on Karasuma’s smartphone. The person Kazama turns to for help then, is a former con artist-turned-magician who he used to study under, Himura Akira (Minamino Yoko). Himura teaches them the arts of trickery and together with Anna, Kazama sneaks into the illegal gambling den, however, the evil clutches of Kan Ken quickly draw near to them there...
Kan Ken’s goal is finally revealed! And, who is the person holding Anna’s father captive? As the outline of the truth behind the incident 20 years prior is exposed, the deep bond between Kazama and Kurita unexpectedly starts to crack! Suspense kicks into gear at once, as the curtain of “Nemesis Season2” lifts! (Translated from NTV official website)